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Category:GO:0038023 ! signaling receptor activity
name: signaling receptor activity
namespace: molecular_function
def: "Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:bf, GOC:signaling]
comment: Note that this term and its child terms are intended for receptors that are directly coupled to a signal transduction pathway. This term should therefore not be used to annotate decoy receptors and other proteins that bind a signal but do not pass the signal on. This term can be used to annotate dependence receptors that transduce a signal when a ligand is withdrawn (in this case, signal withdrawal is considered to be the initiating signal), or receptors that signal at a basal level in the absence of a bound agonist. For receptors that mediate transport of a substance into the cell by receptor-mediated endocytosis, consider instead the term 'cargo receptor activity ; GO:0038024' and its children.
synonym: "receptor activity involved in signal transduction" EXACT [GOC:bf]
synonym: "signalling receptor activity" EXACT [GOC:mah]
is_a: GO:0004871 ! signal transducer activity
is_a: GO:0004872 ! receptor activity
AmiGO
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Child Terms
This term has the following 21 child terms, out of 21 total.
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Pages in category "GO:0038023 ! signaling receptor activity"
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