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Category:GO:0036378 ! calcitriol biosynthetic process from calciol
name: calcitriol biosynthetic process from calciol
namespace: biological_process
def: "Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol." [GOC:BHF, GOC:rl, PMID:17426122, PMID:20511049]
synonym: "1alpha,25(OH)2D3 biosynthesis" BROAD [CHEBI:17823]
synonym: "1alpha,25-dihydroxycholecalciferol biosynthesis" BROAD [CHEBI:17823]
synonym: "1alpha,25-dihydroxyvitamin D3 biosynthesis" BROAD [CHEBI:17823]
synonym: "calcitriol biosynthesis from calciol" EXACT [GOC:bf]
synonym: "vitamin D3 activation" EXACT [GOC:bf, PMID:20506379]
is_a: GO:0042368 ! vitamin D biosynthetic process
is_a: GO:0046173 ! polyol biosynthetic process
is_a: GO:0070640 ! vitamin D3 metabolic process
AmiGO
<GOterm>GO:0036378</GOterm>
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This category has the following 2 subcategories, out of 2 total.
