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Category:GO:0036130 ! prostaglandin H2 endoperoxidase reductase activity
name: prostaglandin H2 endoperoxidase reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate)." [GOC:mw, KEGG_REACTION:R02264, PMID:10622721, PMID:14979715, PMID:16475787]
synonym: "PGH2 9,11-endoperoxidase" EXACT [PMID:12664595]
synonym: "PGH2 9-,11-endoperoxide reductase" EXACT [PMID:12432932]
xref: KEGG_REACTION:R02264
xref: RHEA:45312
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
relationship: part_of: GO:0006693 ! prostaglandin metabolic process
AmiGO
<GOterm>GO:0036130</GOterm>
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