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Category:GO:0035632 ! mitochondrial prohibitin complex
name: mitochondrial prohibitin complex
namespace: cellular_component
def: "A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death." [GOC:kmv, PMID:12237468, PMID:21164222]
synonym: "mitochondrial inner membrane prohibitin complex" EXACT [GOC:bf]
is_a: GO:0043234 ! protein complex
is_a: GO:0044455 ! mitochondrial membrane part
relationship:part_of: GO:0005743 ! mitochondrial inner membrane
AmiGO
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