Category:GO:0035105 ! sterol regulatory element binding protein import into nucleus

name: sterol regulatory element binding protein import into nucleus
namespace: biological_process
def: "The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525]
comment: Note that 'translocation' is sometimes used in the literature to refer to the entire process of protein import into the nucleus, but in GO refers specifically to the step in which a cargo-carrier protein complex moves through the nuclear pore complex.
synonym: "SREBP import into nucleus" EXACT [GOC:mah]
synonym: "SREBP nuclear translocation" NARROW [GOC:mah]
synonym: "sterol regulatory element binding protein nuclear translocation" NARROW [GOC:mah]
is_a: GO:0006606 ! protein import into nucleus
relationship:part_of: GO:0032933 ! SREBP-mediated signaling pathway

AmiGO

Child Terms

This term has only the following child term.

• [  ] GO:0006993 ! sterol regulatory element binding protein import into nucleus involved in sterol depletion response

Pages in category "GO:0035105 ! sterol regulatory element binding protein import into nucleus"

The following 3 pages are in this category, out of 3 total.

H

• HUMAN:LMNA

M

• MGI:Lmna
• MOUSE:LMNA