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Category:GO:0033783 ! 25-hydroxycholesterol 7alpha-hydroxylase activity
name: 25-hydroxycholesterol 7alpha-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O." [EC:1.14.13.100]
synonym: "25-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.100]
synonym: "cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" EXACT [EC:1.14.13.100]
synonym: "CYP7B1" RELATED [EC:1.14.13.100]
synonym: "CYP7B1 oxysterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.100]
xref: EC:1.14.13.100
xref: MetaCyc:RXN-7980
xref: MetaCyc:RXN-7981
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
AmiGO
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