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Category:GO:0033176 ! proton-transporting V-type ATPase complex
name: proton-transporting V-type ATPase complex
namespace: cellular_component
def: "A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane." [GOC:mah, ISBN:0716743663, PMID:16449553]
synonym: "hydrogen-translocating V-type ATPase complex" EXACT []
is_a: GO:0016469 ! proton-transporting two-sector ATPase complex
AmiGO
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