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Category:GO:0033011 ! perinuclear theca
name: perinuclear theca
namespace: cellular_component
def: "A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins." [PMID:17289678, PMID:8025156]
is_a: GO:0005856 ! cytoskeleton
is_a: GO:0044444 ! cytoplasmic part
relationship:part_of: GO:0048471 ! perinuclear region of cytoplasm
AmiGO
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