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Category:GO:0032422 ! purine-rich negative regulatory element binding
name: purine-rich negative regulatory element binding
namespace: molecular_function
def: "Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes." [GOC:mah, PMID:9819411]
synonym: "PNR element binding" BROAD []
is_a: GO:0043565 ! sequence-specific DNA binding
is_a: GO:0044212 ! transcription regulatory region DNA binding
AmiGO
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