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Category:GO:0031511 ! Mis6-Sim4 complex
name: Mis6-Sim4 complex
namespace: cellular_component
def: "A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human." [GOC:vw, PMID:12719471, PMID:15897182]
synonym: "Mis6 centromere subcomplex" NARROW []
synonym: "Mis6-Mal2-Sim4 centromere complex" EXACT [GOC:vw, PMID:21445296]
synonym: "Sim4 complex" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044427 ! chromosomal part
relationship:part_of: GO:0000939 ! condensed chromosome inner kinetochore
AmiGO
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