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Category:GO:0031264 ! death-inducing signaling complex
name: death-inducing signaling complex
namespace: cellular_component
def: "A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor." [GOC:mtg_apoptosis, PMID:12628743, PMID:12655293, PMID:8521815]
subset: goslim_pir
synonym: "death receptor-induced signaling complex" EXACT []
synonym: "death receptor-induced signalling complex" EXACT []
synonym: "death-inducing signalling complex" EXACT []
synonym: "DISC" EXACT []
synonym: "DISC protein complex" EXACT []
xref: Wikipedia:Death-inducing_signaling_complex
is_a: GO:0043234 ! protein complex
is_a: GO:0044459 ! plasma membrane part
AmiGO
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This term has the following 2 child terms, out of 2 total.
