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Category:GO:0031261 ! DNA replication preinitiation complex
name: DNA replication preinitiation complex
namespace: cellular_component
def: "A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present." [GOC:vw, PMID:12694535, PMID:15194812]
synonym: "pre-IC" EXACT []
is_a: GO:0032993 ! protein-DNA complex
is_a: GO:0044451 ! nucleoplasm part
AmiGO
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