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Category:GO:0031080 ! nuclear pore outer ring
name: nuclear pore outer ring
namespace: cellular_component
def: "A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates)." [GOC:dgf, PMID:18046406, PMID:19524430, PMID:20947011, PMID:22419078]
synonym: "Nup107-120 complex" EXACT []
synonym: "Nup107-160 complex" EXACT []
synonym: "Nup84 complex" EXACT []
is_a: GO:0140513 ! nuclear protein-containing complex
relationship: part_of: GO:0005643 ! nuclear pore
AmiGO
<GOterm>GO:0031080</GOterm>
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