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Category:GO:0030877 ! beta-catenin destruction complex
name: beta-catenin destruction complex
namespace: cellular_component
def: "A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome." [PMID:14600025]
synonym: "beta-catenin degradation complex" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044444 ! cytoplasmic part
AmiGO
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