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Category:GO:0030057 ! desmosome
name: desmosome
namespace: cellular_component
def: "A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181]
synonym: "macula adherens" EXACT []
synonym: "spot desmosome" EXACT []
xref: Wikipedia:Desmosome
is_a: GO:0005911 ! cell-cell junction
is_a: GO:0070161 ! anchoring junction
AmiGO
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