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Category:GO:0017136 ! NAD-dependent histone deacetylase activity
name: NAD-dependent histone deacetylase activity
namespace: molecular_function
def: "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone." [EC:3.5.1.17, EC:3.5.1.98, RHEA:24551]
synonym: "SIR2" RELATED []
is_a: GO:0004407 ! histone deacetylase activity
is_a: GO:0034979 ! NAD-dependent protein deacetylase activity
AmiGO
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