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Category:GO:0017108 ! 5'-flap endonuclease activity
name: 5'-flap endonuclease activity
namespace: molecular_function
def: "Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis." [PMID:9778254]
synonym: "5' flap endonuclease activity" EXACT []
xref: Reactome:REACT_106924 "Removal of remaining Flap from the C-strand, Bos taurus"
xref: Reactome:REACT_110586 "Removal of remaining Flap from the C-strand, Xenopus tropicalis"
xref: Reactome:REACT_110813 "Removal of remaining Flap, Mus musculus"
xref: Reactome:REACT_2024 "Removal of remaining Flap, Homo sapiens"
xref: Reactome:REACT_2189 "Cleavage of flap structures, Homo sapiens"
xref: Reactome:REACT_28301 "Removal of remaining Flap from the C-strand, Danio rerio"
xref: Reactome:REACT_29570 "Cleavage of flap structures, Bos taurus"
xref: Reactome:REACT_29736 "Removal of remaining Flap from the C-strand, Oryza sativa"
xref: Reactome:REACT_32687 "Cleavage of flap structures, Danio rerio"
xref: Reactome:REACT_33124 "Removal of remaining Flap, Danio rerio"
xref: Reactome:REACT_79626 "Removal of remaining Flap, Oryza sativa"
xref: Reactome:REACT_7975 "Removal of remaining Flap from the C-strand, Homo sapiens"
xref: Reactome:REACT_80191 "Cleavage of flap structures, Arabidopsis thaliana"
xref: Reactome:REACT_80899 "Removal of remaining Flap, Xenopus tropicalis"
xref: Reactome:REACT_81149 "Cleavage of flap structures, Oryza sativa"
xref: Reactome:REACT_81201 "Removal of remaining Flap from the C-strand, Mus musculus"
xref: Reactome:REACT_82521 "Removal of remaining Flap, Schizosaccharomyces pombe"
xref: Reactome:REACT_88163 "Removal of remaining Flap, Bos taurus"
xref: Reactome:REACT_88514 "Cleavage of flap structures, Rattus norvegicus"
xref: Reactome:REACT_88760 "Removal of remaining Flap from the C-strand, Sus scrofa"
xref: Reactome:REACT_90619 "Cleavage of flap structures, Mus musculus"
xref: Reactome:REACT_92339 "Removal of remaining Flap from the C-strand, Rattus norvegicus"
xref: Reactome:REACT_94506 "Removal of remaining Flap, Sus scrofa"
xref: Reactome:REACT_96177 "Removal of remaining Flap, Arabidopsis thaliana"
xref: Reactome:REACT_96276 "Removal of remaining Flap from the C-strand, Schizosaccharomyces pombe"
xref: Reactome:REACT_97146 "Removal of remaining Flap from the C-strand, Arabidopsis thaliana"
xref: Reactome:REACT_97888 "Cleavage of flap structures, Xenopus tropicalis"
xref: Reactome:REACT_98183 "Removal of remaining Flap, Rattus norvegicus"
xref: Reactome:REACT_98512 "Cleavage of flap structures, Sus scrofa"
is_a: GO:0016888 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters
is_a: GO:0048256 ! flap endonuclease activity
AmiGO
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