Category:GO:0017101 ! aminoacyl-tRNA synthetase multienzyme complex

name: aminoacyl-tRNA synthetase multienzyme complex
namespace: cellular_component
def: "A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates." [GOC:jl, PMID:16169847]
synonym: "aminoacyl-tRNA synthetase complex" EXACT []
synonym: "multisynthetase complex" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044424 ! intracellular part

AmiGO

Pages in category "GO:0017101 ! aminoacyl-tRNA synthetase multienzyme complex"

The following 12 pages are in this category, out of 12 total.