GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0016975 ! obsolete alpha-2 macroglobulin
This GO term has been obsoleted.
Do not annotate to it.
id: GO:0016975
name: obsolete alpha-2 macroglobulin
namespace: molecular_function
def: "OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates." [ISBN:0198547684]
comment: This term was made obsolete because it represents a gene product.
synonym: "alpha-2 macroglobulin" EXACT []
is_obsolete: true
replaced_by: GO:0004866 ! endopeptidase inhibitor activity
AmiGO
<GOterm>GO:0016975</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
This category currently contains no pages or media.
