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Category:GO:0016556 ! mRNA modification
name: mRNA modification
namespace: biological_process
alt_id:GO:0006381
def: "The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically." [GOC:curators]
comment: The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.
subset: gosubset_prok
synonym: "mRNA editing" NARROW [GOC:dph, GOC:hjd, GOC:tb]
xref: Reactome:REACT_100618 "mRNA Editing, Taeniopygia guttata"
xref: Reactome:REACT_100905 "mRNA Editing, Oryza sativa"
xref: Reactome:REACT_113194 "mRNA Editing, Caenorhabditis elegans"
xref: Reactome:REACT_114458 "mRNA Editing, Schizosaccharomyces pombe"
xref: Reactome:REACT_114695 "mRNA Editing, Saccharomyces cerevisiae"
xref: Reactome:REACT_1757 "mRNA Editing, Homo sapiens"
xref: Reactome:REACT_28944 "mRNA Editing, Mus musculus"
xref: Reactome:REACT_29117 "mRNA Editing, Sus scrofa"
xref: Reactome:REACT_33029 "mRNA Editing, Gallus gallus"
xref: Reactome:REACT_33947 "mRNA Editing, Xenopus tropicalis"
xref: Reactome:REACT_47394 "mRNA Editing, Dictyostelium discoideum"
xref: Reactome:REACT_81752 "mRNA Editing, Danio rerio"
xref: Reactome:REACT_85035 "mRNA Editing, Arabidopsis thaliana"
xref: Reactome:REACT_91114 "mRNA Editing, Canis familiaris"
xref: Reactome:REACT_91790 "mRNA Editing, Drosophila melanogaster"
xref: Reactome:REACT_94500 "mRNA Editing, Bos taurus"
xref: Reactome:REACT_98313 "mRNA Editing, Rattus norvegicus"
is_a: GO:0009451 ! RNA modification
is_a: GO:0016071 ! mRNA metabolic process
AmiGO
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This term has the following 5 child terms, out of 5 total.
