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Category:GO:0016513 ! core-binding factor complex
name: core-binding factor complex
namespace: cellular_component
def: "A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit." [PMID:15156179, PMID:8497254]
synonym: "AML1 complex" NARROW []
synonym: "CBF complex" EXACT []
synonym: "PEPB2 complex" NARROW []
is_a: GO:0005667 ! transcription factor complex
AmiGO
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