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Category:GO:0016509 ! long-chain-3-hydroxyacyl-CoA dehydrogenase activity
name: long-chain-3-hydroxyacyl-CoA dehydrogenase activity
namespace: molecular_function
def: "Catalysis of the reaction: a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD+ = a long-chain 3-oxo-fatty acyl-CoA + H+ + NADH. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons." [EC:1.1.1.211, GOC:pde, RHEA:52656]
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
synonym: "beta-hydroxyacyl-CoA dehydrogenase activity" RELATED [EC:1.1.1.211]
synonym: "LCHAD" RELATED [EC:1.1.1.211]
synonym: "long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity" RELATED [EC:1.1.1.211]
synonym: "long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity" RELATED [EC:1.1.1.211]
xref: EC:1.1.1.211
xref: MetaCyc:1.1.1.211-RXN
xref: RHEA:52656
is_a: GO:0003857 ! 3-hydroxyacyl-CoA dehydrogenase activity
AmiGO
<GOterm>GO:0016509</GOterm>
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