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Category:GO:0016442 ! RISC complex
name: RISC complex
namespace: cellular_component
alt_id: GO:0035068
def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation." [PMID:10749213, PMID:15145345]
synonym: "micro-ribonucleoprotein complex" RELATED []
synonym: "miRNP complex" RELATED []
synonym: "RNA-induced silencing complex" EXACT []
xref: Wikipedia:RNA-induced_silencing_complex
is_a: GO:0031332 ! RNAi effector complex
AmiGO
<GOterm>GO:0016442</GOterm>
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