Category:GO:0016251 ! general RNA polymerase II transcription factor activity

This GO term has been obsoleted. Do not annotate to it.

id: GO:0016251
name: general RNA polymerase II transcription factor activity
namespace: molecular_function
alt_id:GO:0003703
def: "OBSOLETE. Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBF)." [PMID:10384286, PMID:9774831]
comment: This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.
is_obsolete: true
consider: GO:0000981 ! sequence-specific DNA binding RNA polymerase II transcription factor activity
consider: GO:0000991 ! core RNA polymerase II binding transcription factor activity
consider: GO:0001076 ! RNA polymerase II transcription factor binding transcription factor activity
consider: GO:0006366 ! transcription from RNA polymerase II promoter

AmiGO

Child Terms

This term has only the following child term.

• [  ] GO:0016455 ! RNA polymerase II transcription mediator activity

Pages in category "GO:0016251 ! general RNA polymerase II transcription factor activity"

The following 12 pages are in this category, out of 12 total.