Category:GO:0016245 ! hyperphosphorylation of RNA polymerase II C-terminal domain

name: hyperphosphorylation of RNA polymerase II C-terminal domain
namespace: biological_process
def: "The production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, as a result of activation of kinases, deactivation of phosphatases, or both. This phosphorylation occurs during the initiation phase and is required for the transition to the elongation phase. Specific types of phosphorylation within the CTD are associated with recruitment of complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex." [GOC:krc, PMID:15964991]
xref: Reactome:448704 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:469826 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:487519 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:507480 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:517464 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:526337 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:531170 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:536545 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:542266 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:547612 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:552216 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:557806 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:568423 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:581625 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:592522 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:595357 "RNA Pol II CTD phosphorylation and interaction with CE"
xref: Reactome:77075 "RNA Pol II CTD phosphorylation and interaction with CE"
is_a: GO:0006357 ! regulation of transcription from RNA polymerase II promoter
is_a: GO:0070816 ! phosphorylation of RNA polymerase II C-terminal domain
relationship:part_of: GO:0006367 ! transcription initiation from RNA polymerase II promoter

AmiGO