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Category:GO:0016206 ! catechol O-methyltransferase activity
name: catechol O-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol." [EC:2.1.1.6]
subset: gosubset_prok
synonym: "catechol methyltransferase activity" EXACT [EC:2.1.1.6]
synonym: "catecholamine O-methyltransferase activity" EXACT [EC:2.1.1.6]
synonym: "COMT I" RELATED [EC:2.1.1.6]
synonym: "COMT II" RELATED [EC:2.1.1.6]
synonym: "MB-COMT (membrane-bound form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6]
synonym: "S-adenosyl-L-methionine:catechol O-methyltransferase activity" EXACT [EC:2.1.1.6]
synonym: "S-COMT (soluble form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6]
xref: EC:2.1.1.6
xref: MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN
xref: Reactome:REACT_101180 "3,4-dihydroxybenzoate can be O-methylated, Mycobacterium tuberculosis"
xref: Reactome:REACT_106126 "3,4-dihydroxybenzoate can be O-methylated, Taeniopygia guttata"
xref: Reactome:REACT_107035 "3,4-dihydroxybenzoate can be O-methylated, Mus musculus"
xref: Reactome:REACT_107702 "3,4-dihydroxybenzoate can be O-methylated, Canis familiaris"
xref: Reactome:REACT_108398 "3,4-dihydroxybenzoate can be O-methylated, Rattus norvegicus"
xref: Reactome:REACT_110868 "3,4-dihydroxybenzoate can be O-methylated, Schizosaccharomyces pombe"
xref: Reactome:REACT_29223 "3,4-dihydroxybenzoate can be O-methylated, Bos taurus"
xref: Reactome:REACT_29723 "3,4-dihydroxybenzoate can be O-methylated, Xenopus tropicalis"
xref: Reactome:REACT_6885 "3,4-dihydroxybenzoate can be O-methylated, Homo sapiens"
xref: Reactome:REACT_79706 "3,4-dihydroxybenzoate can be O-methylated, Gallus gallus"
xref: Reactome:REACT_80595 "3,4-dihydroxybenzoate can be O-methylated, Sus scrofa"
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
AmiGO
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