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Category:GO:0015468 ! colicin
This GO term has been obsoleted.
Do not annotate to it.
id: GO:0015468
name: colicin
namespace: molecular_function
def: "OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it." [TC:1.C.1.-.-]
comment: This term was made obsolete because it represents a class of gene products.
is_obsolete: true
consider: GO:0005102 ! receptor binding
consider: GO:0005198 ! structural molecule activity
consider: GO:0009405 ! pathogenesis
consider: GO:0019835 ! cytolysis
consider: GO:0046930 ! pore complex
consider: GO:0046931 ! pore complex assembly
consider: GO:0050827 ! toxin receptor binding
AmiGO
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