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Category:GO:0015385 ! sodium:hydrogen antiporter activity
name: sodium:hydrogen antiporter activity
namespace: molecular_function
alt_id:GO:0015502
def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [TC:2.A.35.1.1, TC:2.A.36.-.-]
subset: gosubset_prok
synonym: "pH-dependent sodium:hydrogen antiporter activity" NARROW []
synonym: "pH-dependent sodium:proton antiporter activity" NARROW []
synonym: "sodium/hydrogen antiporter activity" EXACT []
synonym: "sodium:hydrogen exchange activity" EXACT []
synonym: "sodium:hydrogen exchanger" EXACT []
synonym: "sodium:proton antiporter activity" EXACT []
xref: Reactome:REACT_100313 "Na+/H+ exchanger transport (at cell membrane), Canis familiaris"
xref: Reactome:REACT_100581 "Na+/H+ exchanger transport (at trans-golgi membrane), Arabidopsis thaliana"
xref: Reactome:REACT_100724 "Na+/H+ exchanger transport (at cell membrane), Mycobacterium tuberculosis"
xref: Reactome:REACT_101156 "Na+/H+ exchanger transport (at late endosome membrane), Oryza sativa"
xref: Reactome:REACT_102032 "Na+/H+ exchanger transport (at late endosome membrane), Gallus gallus"
xref: Reactome:REACT_102112 "Na+/H+ exchanger transport (at late endosome membrane), Escherichia coli"
xref: Reactome:REACT_102864 "Na+/H+ exchanger transport (at trans-golgi membrane), Mus musculus"
xref: Reactome:REACT_102894 "Na+/H+ exchanger transport (at trans-golgi membrane), Oryza sativa"
xref: Reactome:REACT_105719 "Na+/H+ exchanger transport (at trans-golgi membrane), Staphylococcus aureus N315"
xref: Reactome:REACT_106807 "Na+/H+ exchanger transport (at cell membrane), Gallus gallus"
xref: Reactome:REACT_107375 "Na+/H+ exchanger transport (at cell membrane), Sus scrofa"
xref: Reactome:REACT_107865 "Na+/H+ exchanger transport (at early endosome membrane), Bos taurus"
xref: Reactome:REACT_108868 "Na+/H+ exchanger transport (at late endosome membrane), Taeniopygia guttata"
xref: Reactome:REACT_109095 "Na+/H+ exchanger transport (at early endosome membrane), Drosophila melanogaster"
xref: Reactome:REACT_109433 "Na+/H+ exchanger transport (at late endosome membrane), Staphylococcus aureus N315"
xref: Reactome:REACT_110267 "Na+/H+ exchanger transport (at early endosome membrane), Caenorhabditis elegans"
xref: Reactome:REACT_110836 "Na+/H+ exchanger transport (at cell membrane), Mus musculus"
xref: Reactome:REACT_110863 "Na+/H+ exchanger transport (at cell membrane), Xenopus tropicalis"
xref: Reactome:REACT_112054 "Na+/H+ exchanger transport (at early endosome membrane), Gallus gallus"
xref: Reactome:REACT_19218 "Na+/H+ exchanger transport (at trans-golgi membrane), Homo sapiens"
xref: Reactome:REACT_19224 "Na+/H+ exchanger transport (at cell membrane), Homo sapiens"
xref: Reactome:REACT_19253 "Na+/H+ exchanger transport (at early endosome membrane), Homo sapiens"
xref: Reactome:REACT_19303 "Na+/H+ exchanger transport (at late endosome membrane), Homo sapiens"
xref: Reactome:REACT_28080 "Na+/H+ exchanger transport (at late endosome membrane), Saccharomyces cerevisiae"
xref: Reactome:REACT_28922 "Na+/H+ exchanger transport (at late endosome membrane), Schizosaccharomyces pombe"
xref: Reactome:REACT_30436 "Na+/H+ exchanger transport (at trans-golgi membrane), Danio rerio"
xref: Reactome:REACT_30713 "Na+/H+ exchanger transport (at early endosome membrane), Danio rerio"
xref: Reactome:REACT_32407 "Na+/H+ exchanger transport (at cell membrane), Drosophila melanogaster"
xref: Reactome:REACT_32466 "Na+/H+ exchanger transport (at early endosome membrane), Taeniopygia guttata"
xref: Reactome:REACT_33295 "Na+/H+ exchanger transport (at late endosome membrane), Xenopus tropicalis"
xref: Reactome:REACT_34009 "Na+/H+ exchanger transport (at late endosome membrane), Rattus norvegicus"
xref: Reactome:REACT_34239 "Na+/H+ exchanger transport (at cell membrane), Danio rerio"
xref: Reactome:REACT_48026 "Na+/H+ exchanger transport (at trans-golgi membrane), Caenorhabditis elegans"
xref: Reactome:REACT_77239 "Na+/H+ exchanger transport (at trans-golgi membrane), Sus scrofa"
xref: Reactome:REACT_77347 "Na+/H+ exchanger transport (at trans-golgi membrane), Mycobacterium tuberculosis"
xref: Reactome:REACT_77622 "Na+/H+ exchanger transport (at early endosome membrane), Staphylococcus aureus N315"
xref: Reactome:REACT_77750 "Na+/H+ exchanger transport (at late endosome membrane), Caenorhabditis elegans"
xref: Reactome:REACT_78497 "Na+/H+ exchanger transport (at early endosome membrane), Schizosaccharomyces pombe"
xref: Reactome:REACT_78841 "Na+/H+ exchanger transport (at cell membrane), Taeniopygia guttata"
xref: Reactome:REACT_80328 "Na+/H+ exchanger transport (at early endosome membrane), Canis familiaris"
xref: Reactome:REACT_80427 "Na+/H+ exchanger transport (at trans-golgi membrane), Drosophila melanogaster"
xref: Reactome:REACT_81164 "Na+/H+ exchanger transport (at late endosome membrane), Mus musculus"
xref: Reactome:REACT_81214 "Na+/H+ exchanger transport (at early endosome membrane), Mus musculus"
xref: Reactome:REACT_81645 "Na+/H+ exchanger transport (at trans-golgi membrane), Taeniopygia guttata"
xref: Reactome:REACT_83014 "Na+/H+ exchanger transport (at late endosome membrane), Arabidopsis thaliana"
xref: Reactome:REACT_83758 "Na+/H+ exchanger transport (at late endosome membrane), Sus scrofa"
xref: Reactome:REACT_84369 "Na+/H+ exchanger transport (at late endosome membrane), Drosophila melanogaster"
xref: Reactome:REACT_85599 "Na+/H+ exchanger transport (at early endosome membrane), Sus scrofa"
xref: Reactome:REACT_86696 "Na+/H+ exchanger transport (at early endosome membrane), Mycobacterium tuberculosis"
xref: Reactome:REACT_87561 "Na+/H+ exchanger transport (at trans-golgi membrane), Gallus gallus"
xref: Reactome:REACT_89780 "Na+/H+ exchanger transport (at trans-golgi membrane), Bos taurus"
xref: Reactome:REACT_90215 "Na+/H+ exchanger transport (at trans-golgi membrane), Canis familiaris"
xref: Reactome:REACT_90329 "Na+/H+ exchanger transport (at early endosome membrane), Xenopus tropicalis"
xref: Reactome:REACT_91466 "Na+/H+ exchanger transport (at early endosome membrane), Saccharomyces cerevisiae"
xref: Reactome:REACT_92179 "Na+/H+ exchanger transport (at cell membrane), Escherichia coli"
xref: Reactome:REACT_92386 "Na+/H+ exchanger transport (at late endosome membrane), Mycobacterium tuberculosis"
xref: Reactome:REACT_92389 "Na+/H+ exchanger transport (at trans-golgi membrane), Schizosaccharomyces pombe"
xref: Reactome:REACT_92390 "Na+/H+ exchanger transport (at early endosome membrane), Oryza sativa"
xref: Reactome:REACT_92820 "Na+/H+ exchanger transport (at trans-golgi membrane), Saccharomyces cerevisiae"
xref: Reactome:REACT_93564 "Na+/H+ exchanger transport (at early endosome membrane), Escherichia coli"
xref: Reactome:REACT_94624 "Na+/H+ exchanger transport (at late endosome membrane), Canis familiaris"
xref: Reactome:REACT_94723 "Na+/H+ exchanger transport (at trans-golgi membrane), Rattus norvegicus"
xref: Reactome:REACT_95936 "Na+/H+ exchanger transport (at cell membrane), Rattus norvegicus"
xref: Reactome:REACT_96090 "Na+/H+ exchanger transport (at cell membrane), Caenorhabditis elegans"
xref: Reactome:REACT_96181 "Na+/H+ exchanger transport (at early endosome membrane), Arabidopsis thaliana"
xref: Reactome:REACT_96627 "Na+/H+ exchanger transport (at trans-golgi membrane), Escherichia coli"
xref: Reactome:REACT_96669 "Na+/H+ exchanger transport (at cell membrane), Staphylococcus aureus N315"
xref: Reactome:REACT_97077 "Na+/H+ exchanger transport (at late endosome membrane), Bos taurus"
xref: Reactome:REACT_97109 "Na+/H+ exchanger transport (at trans-golgi membrane), Dictyostelium discoideum"
xref: Reactome:REACT_98020 "Na+/H+ exchanger transport (at trans-golgi membrane), Xenopus tropicalis"
xref: Reactome:REACT_99016 "Na+/H+ exchanger transport (at cell membrane), Bos taurus"
xref: Reactome:REACT_99336 "Na+/H+ exchanger transport (at early endosome membrane), Rattus norvegicus"
is_a: GO:0005451 ! monovalent cation:hydrogen antiporter activity
is_a: GO:0015081 ! sodium ion transmembrane transporter activity
AmiGO
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