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Category:GO:0015176 ! holin
This GO term has been obsoleted.
Do not annotate to it.
id: GO:0015176
name: holin
namespace: molecular_function
def: "OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases." [TC:1.A.38.-.-]
comment: This term was made obsolete because it represents a class of gene products.
is_obsolete: true
consider: GO:0008565 ! protein transporter activity
consider: GO:0019835 ! cytolysis
AmiGO
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