GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0008384 ! IkappaB kinase activity
name: IkappaB kinase activity
namespace: molecular_function
def: "Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein." [EC:2.7.11.10]
comment: Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.
synonym: "ATP:IkappaB protein phosphotransferase activity" RELATED [EC:2.7.11.10]
synonym: "CHUK" RELATED [EC:2.7.11.10]
synonym: "IKBKA" RELATED [EC:2.7.11.10]
synonym: "IKBKB" RELATED [EC:2.7.11.10]
synonym: "IKK" RELATED [EC:2.7.11.10]
synonym: "IKK-1" RELATED [EC:2.7.11.10]
synonym: "IKK-2" RELATED [EC:2.7.11.10]
synonym: "inhibitor of NF-kappaB kinase activity" RELATED [EC:2.7.11.10]
synonym: "inhibitor of NFkappaB kinase activity" RELATED [EC:2.7.11.10]
synonym: "STK12" RELATED [EC:2.7.11.10]
synonym: "TANK-binding kinase 1 activity" NARROW [EC:2.7.11.10]
synonym: "TBK1" RELATED [EC:2.7.11.10]
xref: EC:2.7.11.10
xref: MetaCyc:2.7.11.10-RXN
xref: RHEA:19073
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of: GO:0007252 ! I-kappaB phosphorylation
AmiGO
<GOterm>GO:0008384</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
