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Category:GO:0008349 ! MAP kinase kinase kinase kinase activity
name: MAP kinase kinase kinase kinase activity
namespace: molecular_function
def: "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli." [GOC:bf, PMID:11790549]
synonym: "MAP4K activity" EXACT [PMID:20811974]
synonym: "MAPKKKK" EXACT []
xref: EC:2.7.11.-
is_a: GO:0004702 ! receptor signaling protein serine/threonine kinase activity
AmiGO
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