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Category:GO:0008282 ! ATP-sensitive potassium channel complex
name: ATP-sensitive potassium channel complex
namespace: cellular_component
def: "A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.2 subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SUR1 subunit stimulates channel activity." [PMID:16308567, PMID:16956886]
is_a: GO:0034702 ! ion channel complex
is_a: GO:0044459 ! plasma membrane part
relationship:part_of: GO:0005887 ! integral to plasma membrane
AmiGO
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