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Category:GO:0008278 ! cohesin complex
name: cohesin complex
namespace: cellular_component
alt_id:GO:0008279
alt_id:GO:0043222
def: "A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3)." [GOC:sp, PMID:9887095]
subset: goslim_pir
synonym: "14S cohesin" NARROW []
synonym: "SMC complex" RELATED []
synonym: "SMC/kleisin ring complex" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044427 ! chromosomal part
relationship:part_of: GO:0000793 ! condensed chromosome
AmiGO
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