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Category:GO:0008123 ! cholesterol 7-alpha-monooxygenase activity
name: cholesterol 7-alpha-monooxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O." [EC:1.14.13.17]
synonym: "cholesterol 7-alpha-hydroxylase activity" EXACT []
synonym: "cholesterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.17]
synonym: "cholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.17]
synonym: "cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.13.17]
synonym: "cytochrome P450 CYP7A1" NARROW []
xref: EC:1.14.13.17
xref: MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN
xref: Reactome:REACT_10052 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Homo sapiens"
xref: Reactome:REACT_108891 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Bos taurus"
xref: Reactome:REACT_110551 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Xenopus tropicalis"
xref: Reactome:REACT_112443 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Mycobacterium tuberculosis"
xref: Reactome:REACT_113215 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Arabidopsis thaliana"
xref: Reactome:REACT_114538 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Oryza sativa"
xref: Reactome:REACT_114617 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Dictyostelium discoideum"
xref: Reactome:REACT_30185 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Danio rerio"
xref: Reactome:REACT_79018 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Mus musculus"
xref: Reactome:REACT_79632 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Sus scrofa"
xref: Reactome:REACT_81654 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Taeniopygia guttata"
xref: Reactome:REACT_85424 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Rattus norvegicus"
xref: Reactome:REACT_85529 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Gallus gallus"
xref: Reactome:REACT_87361 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Canis familiaris"
xref: RHEA:21815
is_a: GO:0008395 ! steroid hydroxylase activity
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
AmiGO
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Pages in category "GO:0008123 ! cholesterol 7-alpha-monooxygenase activity"
The following 3 pages are in this category, out of 3 total.
