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Category:GO:0006614 ! SRP-dependent cotranslational protein targeting to membrane
name: SRP-dependent cotranslational protein targeting to membrane
namespace: biological_process
def: "The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane." [ISBN:0716731363]
synonym: "ER translocation" BROAD []
synonym: "SRP-dependent cotranslational membrane targeting" EXACT []
synonym: "SRP-dependent cotranslational protein-membrane targeting" EXACT []
is_a: GO:0006613 ! cotranslational protein targeting to membrane
is_a: GO:0045047 ! protein targeting to ER
relationship: has_part: GO:0006412 ! translation
AmiGO
<GOterm>GO:0006614</GOterm>
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