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Category:GO:0006352 ! transcription initiation, DNA-dependent
name: transcription initiation, DNA-dependent
namespace: biological_process
def: "Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription." [GOC:jid, GOC:txnOH, PMID:18280161]
comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
subset: goslim_yeast
subset: gosubset_prok
synonym: "DNA-dependent RNA polymerase complex assembly at promoter" EXACT []
synonym: "initiation of transcription, DNA-dependent" EXACT [GOC:mah]
synonym: "transcription initiation factor activity" RELATED []
is_a: GO:0032774 ! RNA biosynthetic process
relationship:part_of: GO:0006351 ! transcription, DNA-dependent
AmiGO
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Pages in category "GO:0006352 ! transcription initiation, DNA-dependent"
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