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Category:GO:0006296 ! nucleotide-excision repair, DNA incision, 5'-to lesion
name: nucleotide-excision repair, DNA incision, 5'-to lesion
namespace: biological_process
def: "The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage." [GOC:elh, PMID:10197977]
subset: gosubset_prok
synonym: "nucleotide-excision repair, DNA incision, 5' to lesion" EXACT []
xref: Reactome:REACT_101184 "5'-incision of DNA by ERCC1-XPF in GG-NER, Danio rerio"
xref: Reactome:REACT_112122 "5'-incision of DNA by ERCC1-XPF in GG-NER, Xenopus tropicalis"
xref: Reactome:REACT_1311 "5'-incision of DNA by ERCC1-XPF in GG-NER, Homo sapiens"
xref: Reactome:REACT_83838 "5'-incision of DNA by ERCC1-XPF in GG-NER, Rattus norvegicus"
xref: Reactome:REACT_95903 "5'-incision of DNA by ERCC1-XPF in GG-NER, Mus musculus"
is_a: GO:0033683 ! nucleotide-excision repair, DNA incision
AmiGO
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