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Category:GO:0005923 ! tight junction
name: tight junction
namespace: cellular_component
def: "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." [GOC:mah, ISBN:0815332181]
synonym: "zonula occludens" EXACT []
xref: NIF_Subcellular:sao1939999134
xref: Wikipedia:Tight_junction
is_a: GO:0070160 ! occluding junction
relationship:part_of: GO:0043296 ! apical junction complex
AmiGO
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