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Category:GO:0005847 ! mRNA cleavage and polyadenylation specificity factor complex
name: mRNA cleavage and polyadenylation specificity factor complex
namespace: cellular_component
def: "A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal." [PMID:14749727]
synonym: "CFII complex" RELATED []
synonym: "cleavage and polyadenylylation specificity factor activity" RELATED []
synonym: "CPF complex" NARROW []
synonym: "CPSF complex" NARROW []
is_a: GO:0005849 ! mRNA cleavage factor complex
AmiGO
<GOterm>GO:0005847</GOterm>
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