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Category:GO:0005260 ! channel-conductance-controlling ATPase activity
name: channel-conductance-controlling ATPase activity
namespace: molecular_function
def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels." [EC:3.6.3.49]
synonym: "ATP phosphohydrolase (channel-conductance-controlling)" EXACT [EC:3.6.3.49]
synonym: "cystic fibrosis transmembrane conductance regulator" NARROW []
synonym: "cystic-fibrosis membrane-conductance-regulating protein activity" NARROW [EC:3.6.3.49]
xref: EC:3.6.3.49
xref: MetaCyc:3.6.3.49-RXN
is_a: GO:0005254 ! chloride channel activity
is_a: GO:0042626 ! ATPase activity, coupled to transmembrane movement of substances
AmiGO
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