Category:GO:0005242 ! inward rectifier potassium channel activity

name: inward rectifier potassium channel activity
namespace: molecular_function
def: "Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself." [GOC:cb, GOC:mah, PMID:14977398]
subset: gosubset_prok
synonym: "Kir channel activity" EXACT [GOC:cb]
xref: Reactome:REACT_111144 "Activation of ATP sensitive Potassium channels in muscle cells, Homo sapiens"
xref: Reactome:REACT_75758 "Activation of classical Kir channels, Homo sapiens"
xref: Reactome:REACT_75810 "Activation of Potassium transport channels, Homo sapiens"
xref: Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels in neuroendocrine cells, Homo sapiens"
is_a: GO:0005249 ! voltage-gated potassium channel activity
is_a: GO:0015276 ! ligand-gated ion channel activity

AmiGO

Child Terms

This term has the following 2 child terms, out of 2 total.

• [  ] GO:0015272 ! ATP-activated inward rectifier potassium channel activity
• [  ] GO:0015467 ! G-protein activated inward rectifier potassium channel activity

Pages in category "GO:0005242 ! inward rectifier potassium channel activity"

The following 76 pages are in this category, out of 76 total.