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Category:GO:0004843 ! ubiquitin-specific protease activity
name: ubiquitin-specific protease activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of various forms of polymeric ubiquitin sequences." [ISBN:0120793709]
comment: Note that this term is distinguished from 'ubiquitin thiolesterase activity ; GO:0004221' in that it encompasses hydrolysis of any type of bonds formed between ubiquitin and another protein.
subset: gosubset_prok
synonym: "deubiquitinase" EXACT [GOC:vw, PMID:19261746]
synonym: "deubiquitinating enzyme" EXACT [PMID:19188440]
synonym: "deubiquitylase" EXACT [GOC:vw, PMID:15657442]
synonym: "ubiquitin hydrolase activity" EXACT [GOC:rl]
synonym: "UBP" NARROW []
synonym: "UCH2" NARROW []
xref: Reactome:REACT_100631 "FANCD2 deubiquitination by USP1/UAF1, Bos taurus"
xref: Reactome:REACT_115763 "Deubiquitination of RNF41 by P-USP8, Homo sapiens"
xref: Reactome:REACT_115791 "Deubiquitination of FancD2, Gallus gallus"
xref: Reactome:REACT_18350 "FANCD2 deubiquitination by USP1/UAF1, Homo sapiens"
xref: Reactome:REACT_29152 "FANCD2 deubiquitination by USP1/UAF1, Rattus norvegicus"
xref: Reactome:REACT_87211 "FANCD2 deubiquitination by USP1/UAF1, Canis familiaris"
xref: Reactome:REACT_92871 "FANCD2 deubiquitination by USP1/UAF1, Sus scrofa"
xref: Reactome:REACT_95549 "FANCD2 deubiquitination by USP1/UAF1, Mus musculus"
xref: Reactome:REACT_96729 "FANCD2 deubiquitination by USP1/UAF1, Danio rerio"
is_a: GO:0019783 ! small conjugating protein-specific protease activity
AmiGO
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