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Category:GO:0004791 ! thioredoxin-disulfide reductase activity
name: thioredoxin-disulfide reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide." [EC:1.8.1.9, RHEA:20348]
subset: gosubset_prok
synonym: "NADP--thioredoxin reductase activity" EXACT [EC:1.8.1.9]
synonym: "NADPH--thioredoxin reductase activity" EXACT [EC:1.8.1.9]
synonym: "NADPH2:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9]
synonym: "NADPH:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9]
synonym: "thioredoxin disulfide reductase activity" EXACT []
synonym: "thioredoxin reductase (NADPH) activity" EXACT []
synonym: "thioredoxin-disulphide reductase activity" EXACT []
synonym: "thioredoxin:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.9]
xref: EC:1.8.1.9
xref: KEGG:R02016
xref: MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN
xref: Reactome:REACT_101101 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Bos taurus"
xref: Reactome:REACT_102076 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Taeniopygia guttata"
xref: Reactome:REACT_105790 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Rattus norvegicus"
xref: Reactome:REACT_114582 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Caenorhabditis elegans"
xref: Reactome:REACT_1609 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Homo sapiens"
xref: Reactome:REACT_54247 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Mus musculus"
xref: Reactome:REACT_79311 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Gallus gallus"
xref: Reactome:REACT_88338 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Sus scrofa"
xref: Reactome:REACT_94140 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Canis familiaris"
xref: Reactome:REACT_97505 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Xenopus tropicalis"
xref: RHEA:20348
is_a: GO:0016209 ! antioxidant activity
is_a: GO:0016668 ! oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor
AmiGO
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