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Category:GO:0004738 ! pyruvate dehydrogenase activity
name: pyruvate dehydrogenase activity
namespace: molecular_function
def: "Catalysis of the oxidative decarboxylation of pyruvate." [ISBN:0716020094]
subset: gosubset_prok
synonym: "pyruvic acid dehydrogenase activity" EXACT [EC:1.2.4.1]
synonym: "pyruvic dehydrogenase activity" EXACT [EC:1.2.4.1]
xref: MetaCyc:PYRUVOXID-RXN
xref: MetaCyc:RXN0-1134
xref: Reactome:REACT_100036 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Schizosaccharomyces pombe"
xref: Reactome:REACT_102216 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Xenopus tropicalis"
xref: Reactome:REACT_102641 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Arabidopsis thaliana"
xref: Reactome:REACT_108497 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Caenorhabditis elegans"
xref: Reactome:REACT_109621 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Mus musculus"
xref: Reactome:REACT_77363 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Taeniopygia guttata"
xref: Reactome:REACT_81144 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Gallus gallus"
xref: Reactome:REACT_85583 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Danio rerio"
xref: Reactome:REACT_88103 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Sus scrofa"
xref: Reactome:REACT_91141 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Dictyostelium discoideum"
xref: Reactome:REACT_93329 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Canis familiaris"
xref: Reactome:REACT_93801 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Bos taurus"
xref: Reactome:REACT_95829 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Saccharomyces cerevisiae"
xref: Reactome:REACT_96649 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Oryza sativa"
xref: Reactome:REACT_96724 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Rattus norvegicus"
xref: Reactome:REACT_983 "pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+, Homo sapiens"
is_a: GO:0016903 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors
AmiGO
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This term has the following 2 child terms, out of 2 total.
