Category:GO:0004725 ! protein tyrosine phosphatase activity

name: protein tyrosine phosphatase activity
namespace: molecular_function
def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48]
subset: gosubset_prok
synonym: "[phosphotyrosine]protein phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [EC:3.1.3.48]
synonym: "phosphotyrosine histone phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "phosphotyrosine protein phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "phosphotyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "PPT-phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "protein phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "protein-tyrosine-phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "protein-tyrosine-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.48]
synonym: "PTP-phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "PTPase activity" EXACT [EC:3.1.3.48]
synonym: "tyrosine O-phosphate phosphatase activity" EXACT [EC:3.1.3.48]
synonym: "tyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48]
xref: EC:3.1.3.48
xref: MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN
xref: Reactome:REACT_100540 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Mus musculus"
xref: Reactome:REACT_101149 "Dephosphorylation of NCAM1 bound pFyn, Rattus norvegicus"
xref: Reactome:REACT_103930 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Canis familiaris"
xref: Reactome:REACT_104864 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Bos taurus"
xref: Reactome:REACT_105172 "Dephosphorylation of NCAM1 bound pFyn, Bos taurus"
xref: Reactome:REACT_107803 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Gallus gallus"
xref: Reactome:REACT_108914 "Dephosphorylation of CD3-zeta by PD-1 bound phosphatases, Rattus norvegicus"
xref: Reactome:REACT_109643 "Dephosphorylation of NCAM1 bound pFyn, Danio rerio"
xref: Reactome:REACT_111038 "Ptp1b dephosphorylates Jak2, Mus musculus"
xref: Reactome:REACT_111048 "SHP1 (PTPN6) dephosphorylates JAK2, Homo sapiens"
xref: Reactome:REACT_111061 "PTP1B dephosphorylates GHR, Homo sapiens"
xref: Reactome:REACT_111128 "PTP1B dephosphorylates JAK2, Homo sapiens"
xref: Reactome:REACT_111157 "SHP2 dephosphorylates SPRY2, Homo sapiens"
xref: Reactome:REACT_111193 "Shp1 (Ptpn6) dephosphorylates Jak2, Mus musculus"
xref: Reactome:REACT_112085 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Oryza sativa"
xref: Reactome:REACT_112153 "Dephosphorylation of inactive SRC by PTPB1, Drosophila melanogaster"
xref: Reactome:REACT_113070 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Caenorhabditis elegans"
xref: Reactome:REACT_114866 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Arabidopsis thaliana"
xref: Reactome:REACT_115220 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Dictyostelium discoideum"
xref: Reactome:REACT_115381 "Dephosphorylation of inactive SRC by PTPB1, Xenopus tropicalis"
xref: Reactome:REACT_12439 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Homo sapiens"
xref: Reactome:REACT_12446 "Dephosphorylation of Lck-pY505 by CD45, Homo sapiens"
xref: Reactome:REACT_1411 "De-phosphorylation of SHC, Homo sapiens"
xref: Reactome:REACT_15464 "Dephosphorylation of inactive SRC by PTPB1, Homo sapiens"
xref: Reactome:REACT_1810 "De-phosphorylation of IRS, Homo sapiens"
xref: Reactome:REACT_18389 "Dephosphorylation of NCAM1 bound pFyn, Homo sapiens"
xref: Reactome:REACT_18414 "Dephosphorylation of NCAM1 bound pFyn, Homo sapiens"
xref: Reactome:REACT_19146 "Dephosphorylation of CD3-zeta by PD-1 bound phosphatases, Homo sapiens"
xref: Reactome:REACT_22109 "Dephosphorylation of pL1 (Y1176), Homo sapiens"
xref: Reactome:REACT_23816 "SHP1 and SHP2 dephosphorylate Y628 of IL3RB, Homo sapiens"
xref: Reactome:REACT_24939 "Dephosphorylation of STAT1 by SHP2, Homo sapiens"
xref: Reactome:REACT_25185 "Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP, Homo sapiens"
xref: Reactome:REACT_25190 "Dephosphorylation of JAKs by PTPs, Homo sapiens"
xref: Reactome:REACT_25289 "Dephosphorylation of JAK1 by SHP1, Homo sapiens"
xref: Reactome:REACT_25311 "Dephosphorylation of Jaks by Ptps, Mus musculus"
xref: Reactome:REACT_25329 "Dephosphorylation of TYK2 by PTP1B, Homo sapiens"
xref: Reactome:REACT_28210 "Dephosphorylation of inactive SRC by PTPB1, Bos taurus"
xref: Reactome:REACT_32566 "Dephosphorylation of CD3-zeta by PD-1 bound phosphatases, Mus musculus"
xref: Reactome:REACT_34493 "Dephosphorylation of NCAM1 bound pFyn, Gallus gallus"
xref: Reactome:REACT_453 "Insulin receptor de-phosphorylation, Homo sapiens"
xref: Reactome:REACT_77215 "Dephosphorylation of inactive SRC by PTPB1, Danio rerio"
xref: Reactome:REACT_79081 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Drosophila melanogaster"
xref: Reactome:REACT_81528 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Danio rerio"
xref: Reactome:REACT_82080 "Dephosphorylation of Lck-pY505 by CD45, Mus musculus"
xref: Reactome:REACT_83292 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Taeniopygia guttata"
xref: Reactome:REACT_86824 "Dephosphorylation of NCAM1 bound pFyn, Canis familiaris"
xref: Reactome:REACT_88819 "Dephosphorylation of NCAM1 bound pFyn, Taeniopygia guttata"
xref: Reactome:REACT_90186 "Dephosphorylation of NCAM1 bound pFyn, Xenopus tropicalis"
xref: Reactome:REACT_91327 "Dephosphorylation of NCAM1 bound pFyn, Mus musculus"
xref: Reactome:REACT_91510 "Dephosphorylation of inactive SRC by PTPB1, Canis familiaris"
xref: Reactome:REACT_92520 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Xenopus tropicalis"
xref: Reactome:REACT_92699 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Rattus norvegicus"
xref: Reactome:REACT_93431 "Dephosphorylation of inactive SRC by PTPB1, Mus musculus"
xref: Reactome:REACT_93753 "Dephosphorylation of inactive SRC by PTPB1, Sus scrofa"
xref: Reactome:REACT_95709 "Dephosphorylation of Lck-pY505 by CD45, Rattus norvegicus"
xref: Reactome:REACT_97438 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Sus scrofa"
xref: Reactome:REACT_97978 "Dephosphorylation of NCAM1 bound pFyn, Sus scrofa"
xref: Reactome:REACT_98860 "Dephosphorylation of inactive SRC by PTPB1, Rattus norvegicus"
is_a: GO:0004721 ! phosphoprotein phosphatase activity

AmiGO

Child Terms

This term has the following 7 child terms, out of 7 total.

• [  ] GO:0004726 ! non-membrane spanning protein tyrosine phosphatase activity
• [  ] GO:0004727 ! prenylated protein tyrosine phosphatase activity
• [  ] GO:0004728 ! receptor signaling protein tyrosine phosphatase activity
• [  ] GO:0005001 ! transmembrane receptor protein tyrosine phosphatase activity
• [  ] GO:0030945 ! protein tyrosine phosphatase activity, via thiol-phosphate intermediate
• [  ] GO:0030946 ! protein tyrosine phosphatase activity, metal-dependent
• [  ] GO:0033550 ! MAP kinase tyrosine phosphatase activity

Pages in category "GO:0004725 ! protein tyrosine phosphatase activity"

The following 200 pages are in this category, out of 514 total.