Category:GO:0004714 ! transmembrane receptor protein tyrosine kinase activity

name: transmembrane receptor protein tyrosine kinase activity
namespace: molecular_function
def: "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [EC:2.7.10.1, GOC:mah]
subset: gosubset_prok
synonym: "anaplastic lymphoma kinase activity" NARROW [EC:2.7.10.1]
synonym: "ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity" EXACT [EC:2.7.10.1]
synonym: "ATP:protein-tyrosine O-phosphotransferase activity" BROAD [EC:2.7.10.1]
synonym: "Drosophila Eph kinase activity" NARROW [EC:2.7.10.1]
synonym: "ephrin-B3 receptor tyrosine kinase activity" NARROW [EC:2.7.10.1]
synonym: "insulin receptor protein-tyrosine kinase activity" NARROW [EC:2.7.10.1]
synonym: "neurite outgrowth regulating kinase activity" NARROW [EC:2.7.10.1]
synonym: "neurotrophin TRK receptor activity" RELATED []
synonym: "neurotrophin TRKA receptor activity" RELATED []
synonym: "neurotrophin TRKB receptor activity" RELATED []
synonym: "neurotrophin TRKC receptor activity" RELATED []
synonym: "novel oncogene with kinase-domain activity" NARROW [EC:2.7.10.1]
synonym: "receptor protein tyrosine kinase activity" EXACT [EC:2.7.10.1]
synonym: "receptor protein-tyrosine kinase activity" EXACT [EC:2.7.10.1]
synonym: "sevenless receptor activity" RELATED []
xref: EC:2.7.10.1
xref: MetaCyc:2.7.10.1-RXN
xref: Reactome:REACT_100729 "Phosphorylation of IRS, Danio rerio"
xref: Reactome:REACT_101059 "Phosphorylation of SHC, Canis familiaris"
xref: Reactome:REACT_103643 "ARMS is phosphorylated by active TrkA receptor, Mus musculus"
xref: Reactome:REACT_103872 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Gallus gallus"
xref: Reactome:REACT_103996 "Phosphorylation of IRS, Xenopus tropicalis"
xref: Reactome:REACT_104778 "SHC1 phosphorylation by phosphorylated EGFR, Taeniopygia guttata"
xref: Reactome:REACT_105908 "Phosphorylation of SHC, Rattus norvegicus"
xref: Reactome:REACT_106761 "Autophosphorylation of insulin receptor, Gallus gallus"
xref: Reactome:REACT_106931 "Phosphorylation of IRS, Taeniopygia guttata"
xref: Reactome:REACT_106954 "TrkA receptor autophosphorylates, Xenopus tropicalis"
xref: Reactome:REACT_107278 "ARMS is phosphorylated by active TrkA receptor, Danio rerio"
xref: Reactome:REACT_107590 "TrkA phosphorylates PLCG1, Bos taurus"
xref: Reactome:REACT_107902 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Mus musculus"
xref: Reactome:REACT_107918 "SHC1 phosphorylation by phosphorylated EGFR, Gallus gallus"
xref: Reactome:REACT_108158 "TrkA phosphorylates PLCG1, Gallus gallus"
xref: Reactome:REACT_109200 "TRKA phosphorylates IRS, Xenopus tropicalis"
xref: Reactome:REACT_109686 "Autophosphorylation of insulin receptor, Rattus norvegicus"
xref: Reactome:REACT_110882 "TRKA phosphorylates IRS, Gallus gallus"
xref: Reactome:REACT_115842 "Shc, complexed with TrkA, is Tyrosine-phosphorylated, Rattus norvegicus"
xref: Reactome:REACT_116042 "Active Trk phosphorylates PLCG1, Rattus norvegicus"
xref: Reactome:REACT_12003 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Homo sapiens"
xref: Reactome:REACT_12059 "TrkA phosphorylates PLCG1, Homo sapiens"
xref: Reactome:REACT_12063 "FRS2 is phosphorylated by active TrkA receptor, Homo sapiens"
xref: Reactome:REACT_12066 "ARMS is phosphorylated by active TrkA receptor, Homo sapiens"
xref: Reactome:REACT_12434 "TRKA phosphorylates IRS, Homo sapiens"
xref: Reactome:REACT_12592 "SHC1 phosphorylation by phosphorylated EGFR, Homo sapiens"
xref: Reactome:REACT_2015 "Phosphorylation of SHC, Homo sapiens"
xref: Reactome:REACT_2211 "Autophosphorylation of insulin receptor, Homo sapiens"
xref: Reactome:REACT_28481 "Phosphorylation of SHC, Taeniopygia guttata"
xref: Reactome:REACT_29831 "Phosphorylation of IRS, Gallus gallus"
xref: Reactome:REACT_30918 "FRS2 is phosphorylated by active TrkA receptor, Rattus norvegicus"
xref: Reactome:REACT_30960 "FRS2 is phosphorylated by active TrkA receptor, Danio rerio"
xref: Reactome:REACT_31238 "FRS2 is phosphorylated by active TrkA receptor, Mus musculus"
xref: Reactome:REACT_31675 "Autophosphorylation of insulin receptor, Danio rerio"
xref: Reactome:REACT_31943 "ARMS is phosphorylated by active TrkA receptor, Bos taurus"
xref: Reactome:REACT_33793 "Autophosphorylation of insulin receptor, Xenopus tropicalis"
xref: Reactome:REACT_33826 "TrkA phosphorylates PLCG1, Sus scrofa"
xref: Reactome:REACT_33848 "TrkA phosphorylates PLCG1, Canis familiaris"
xref: Reactome:REACT_33897 "TRKA phosphorylates IRS, Bos taurus"
xref: Reactome:REACT_342 "Phosphorylation of IRS, Homo sapiens"
xref: Reactome:REACT_6189 "Autophosphorylation of DINR, Drosophila melanogaster"
xref: Reactome:REACT_77730 "ARMS is phosphorylated by active TrkA receptor, Taeniopygia guttata"
xref: Reactome:REACT_78649 "TRKA phosphorylates IRS, Canis familiaris"
xref: Reactome:REACT_78974 "Phosphorylation of IRS, Bos taurus"
xref: Reactome:REACT_79688 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Xenopus tropicalis"
xref: Reactome:REACT_79822 "ARMS is phosphorylated by active TrkA receptor, Gallus gallus"
xref: Reactome:REACT_80568 "FRS2 is phosphorylated by active TrkA receptor, Bos taurus"
xref: Reactome:REACT_80933 "FRS2 is phosphorylated by active TrkA receptor, Sus scrofa"
xref: Reactome:REACT_82236 "Autophosphorylation of insulin receptor, Canis familiaris"
xref: Reactome:REACT_83172 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Danio rerio"
xref: Reactome:REACT_83536 "TrkA receptor autophosphorylates, Mus musculus"
xref: Reactome:REACT_83584 "TRKA phosphorylates IRS, Danio rerio"
xref: Reactome:REACT_84472 "FRS2 is phosphorylated by active TrkA receptor, Xenopus tropicalis"
xref: Reactome:REACT_84554 "ARMS is phosphorylated by active TrkA receptor, Rattus norvegicus"
xref: Reactome:REACT_85483 "Phosphorylation of SHC, Bos taurus"
xref: Reactome:REACT_86023 "TrkA receptor autophosphorylates, Bos taurus"
xref: Reactome:REACT_86529 "TRKA phosphorylates IRS, Sus scrofa"
xref: Reactome:REACT_87015 "SHC1 phosphorylation by phosphorylated EGFR, Mus musculus"
xref: Reactome:REACT_87046 "FRS2 is phosphorylated by active TrkA receptor, Canis familiaris"
xref: Reactome:REACT_87673 "TRKA phosphorylates IRS, Rattus norvegicus"
xref: Reactome:REACT_87675 "Autophosphorylation of insulin receptor, Taeniopygia guttata"
xref: Reactome:REACT_87906 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Canis familiaris"
xref: Reactome:REACT_88124 "FRS2 is phosphorylated by active TrkA receptor, Gallus gallus"
xref: Reactome:REACT_88945 "Phosphorylation of SHC, Gallus gallus"
xref: Reactome:REACT_89905 "TrkA phosphorylates PLCG1, Danio rerio"
xref: Reactome:REACT_90725 "TrkA phosphorylates PLCG1, Mus musculus"
xref: Reactome:REACT_91057 "SHC1 phosphorylation by phosphorylated EGFR, Xenopus tropicalis"
xref: Reactome:REACT_91150 "Phosphorylation of IRS, Canis familiaris"
xref: Reactome:REACT_91374 "SHC1 phosphorylation by phosphorylated EGFR, Canis familiaris"
xref: Reactome:REACT_91698 "Phosphorylation of SHC, Xenopus tropicalis"
xref: Reactome:REACT_92936 "TrkA receptor autophosphorylates, Danio rerio"
xref: Reactome:REACT_93004 "ARMS is phosphorylated by active TrkA receptor, Canis familiaris"
xref: Reactome:REACT_93045 "SHC1 phosphorylation by phosphorylated EGFR, Danio rerio"
xref: Reactome:REACT_94031 "Autophosphorylation of insulin receptor, Mus musculus"
xref: Reactome:REACT_94040 "Phosphorylation of SHC, Mus musculus"
xref: Reactome:REACT_94130 "TrkA receptor autophosphorylates, Canis familiaris"
xref: Reactome:REACT_94603 "Phosphorylation of IRS, Rattus norvegicus"
xref: Reactome:REACT_94880 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Bos taurus"
xref: Reactome:REACT_94934 "Phosphorylation of SHC, Danio rerio"
xref: Reactome:REACT_95686 "SHC1 phosphorylation by phosphorylated EGFR, Rattus norvegicus"
xref: Reactome:REACT_96548 "ARMS is phosphorylated by active TrkA receptor, Xenopus tropicalis"
xref: Reactome:REACT_96894 "Phosphorylation of IRS, Mus musculus"
xref: Reactome:REACT_97074 "TrkA receptor autophosphorylates, Sus scrofa"
xref: Reactome:REACT_97123 "SHC, complexed with TrkA, is tyrosine-phosphorylated, Sus scrofa"
xref: Reactome:REACT_97498 "TrkA phosphorylates PLCG1, Xenopus tropicalis"
xref: Reactome:REACT_98041 "Autophosphorylation of insulin receptor, Bos taurus"
xref: Reactome:REACT_99216 "TrkA receptor autophosphorylates, Gallus gallus"
xref: Reactome:REACT_9962 "TrkA receptor autophosphorylates, Homo sapiens"
is_a: GO:0004713 ! protein tyrosine kinase activity
is_a: GO:0019199 ! transmembrane receptor protein kinase activity

AmiGO

Child Terms

This term has the following 22 child terms, out of 22 total.

Pages in category "GO:0004714 ! transmembrane receptor protein tyrosine kinase activity"

The following 193 pages are in this category, out of 193 total.