Category:GO:0004709 ! MAP kinase kinase kinase activity

name: MAP kinase kinase kinase activity
namespace: molecular_function
def: "Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases." [PMID:9561267]
synonym: "ATP:protein phosphotransferase (MAPKKKK-activated) activity" EXACT [EC:2.7.11.25]
synonym: "cMos" RELATED [EC:2.7.11.25]
synonym: "cRaf" RELATED [EC:2.7.11.25]
synonym: "MAP3K" RELATED [EC:2.7.11.25, PMID:20811974]
synonym: "MAPKKK activity" EXACT [EC:2.7.11.25]
synonym: "MEK kinase activity" EXACT [EC:2.7.11.25]
synonym: "MEKK" RELATED [EC:2.7.11.25]
synonym: "MEKK1" RELATED [EC:2.7.11.25]
synonym: "MEKK2" RELATED [EC:2.7.11.25]
synonym: "MEKK3" RELATED [EC:2.7.11.25]
synonym: "Mil/Raf" RELATED [EC:2.7.11.25]
synonym: "mitogen-activated protein kinase kinase kinase activity" EXACT [EC:2.7.11.25]
synonym: "MLK-like mitogen-activated protein triple kinase activity" NARROW [EC:2.7.11.25]
synonym: "MLTK" RELATED [EC:2.7.11.25]
synonym: "MLTKa" RELATED [EC:2.7.11.25]
synonym: "MLTKb" RELATED [EC:2.7.11.25]
synonym: "REKS" RELATED [EC:2.7.11.25]
synonym: "STK28" RELATED [EC:2.7.11.25]
xref: EC:2.7.11.25
xref: MetaCyc:2.7.11.25-RXN
xref: Reactome:REACT_105756 "Akt:pCot phosphorylates NIK, Xenopus tropicalis"
xref: Reactome:REACT_107518 "Akt:pCot phosphorylates NIK, Bos taurus"
xref: Reactome:REACT_108303 "Akt:pCot phosphorylates NIK, Mus musculus"
xref: Reactome:REACT_114785 "Akt:pCot phosphorylates NIK, Gallus gallus"
xref: Reactome:REACT_19141 "Akt:pCot phosphorylates NIK, Homo sapiens"
xref: Reactome:REACT_22190 "TAK1 phosphorylates MKK6, Homo sapiens"
xref: Reactome:REACT_22271 "TPL2 phosphorylates MEK1, SEK1, Homo sapiens"
xref: Reactome:REACT_22411 "Tpl2 phosphorylates Mek1, Sek1, Mus musculus"
xref: Reactome:REACT_81738 "Akt:pCot phosphorylates NIK, Rattus norvegicus"
xref: Reactome:REACT_85351 "Akt:pCot phosphorylates NIK, Canis familiaris"
xref: Reactome:REACT_85999 "Akt:pCot phosphorylates NIK, Taeniopygia guttata"
is_a: GO:0004702 ! receptor signaling protein serine/threonine kinase activity

AmiGO

Child Terms

This term has the following 7 child terms, out of 7 total.

• [  ] GO:0004706 ! JUN kinase kinase kinase activity
• [  ] GO:0004710 ! MAP/ERK kinase kinase activity
• [  ] GO:0004710 ! MAPK/ERK kinase kinase activity
• [  ] GO:0038070 ! MAP kinase kinase kinase activity involved in cell wall biogenesis
• [  ] GO:0038073 ! MAP kinase kinase kinase activity involved in conjugation with cellular fusion
• [  ] GO:0038077 ! MAP kinase kinase kinase activity involved in innate immune response
• [  ] GO:0038081 ! MAP kinase kinase kinase activity involved in osmosensory signaling pathway

Pages in category "GO:0004709 ! MAP kinase kinase kinase activity"

The following 47 pages are in this category, out of 47 total.