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Category:GO:0004709 ! MAP kinase kinase kinase activity
name: MAP kinase kinase kinase activity
namespace: molecular_function
alt_id: GO:0004710
def: "Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases." [PMID:9561267]
synonym: "ATP:protein phosphotransferase (MAPKKKK-activated) activity" RELATED [EC:2.7.11.25]
synonym: "cMos" RELATED [EC:2.7.11.25]
synonym: "cRaf" RELATED [EC:2.7.11.25]
synonym: "MAP3K" RELATED [EC:2.7.11.25, PMID:20811974]
synonym: "MAPK/ERK kinase kinase activity" EXACT []
synonym: "MAPKKK activity" RELATED [EC:2.7.11.25]
synonym: "MEK kinase activity" RELATED [EC:2.7.11.25]
synonym: "MEKK" RELATED [EC:2.7.11.25]
synonym: "MEKK activity" EXACT []
synonym: "MEKK1" RELATED [EC:2.7.11.25]
synonym: "MEKK2" RELATED [EC:2.7.11.25]
synonym: "MEKK3" RELATED [EC:2.7.11.25]
synonym: "Mil/Raf" RELATED [EC:2.7.11.25]
synonym: "mitogen-activated protein kinase kinase kinase activity" RELATED [EC:2.7.11.25]
synonym: "MLK-like mitogen-activated protein triple kinase activity" NARROW [EC:2.7.11.25]
synonym: "MLTK" RELATED [EC:2.7.11.25]
synonym: "MLTKa" RELATED [EC:2.7.11.25]
synonym: "MLTKb" RELATED [EC:2.7.11.25]
synonym: "REKS" RELATED [EC:2.7.11.25]
synonym: "STK28" RELATED [EC:2.7.11.25]
xref: EC:2.7.11.25
xref: MetaCyc:2.7.11.25-RXN
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of: GO:0000165 ! MAPK cascade
AmiGO
<GOterm>GO:0004709</GOterm>
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