Category:GO:0004707 ! MAP kinase activity

name: MAP kinase activity
namespace: molecular_function
alt_id:GO:0008338
alt_id:GO:0008339
alt_id:GO:0016908
def: "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684]
synonym: "ATP:protein phosphotransferase (MAPKK-activated) activity" EXACT [EC:2.7.11.24]
synonym: "Dp38" RELATED [EC:2.7.11.24]
synonym: "ERK" RELATED [EC:2.7.11.24]
synonym: "ERK1" EXACT []
synonym: "ERK2" RELATED []
synonym: "extracellular signal-regulated kinase activity" NARROW [EC:2.7.11.24]
synonym: "LeMPK3" RELATED [EC:2.7.11.24]
synonym: "MAP kinase 1 activity" NARROW []
synonym: "MAP kinase 2 activity" NARROW []
synonym: "MAP-2 kinase activity" NARROW [EC:2.7.11.24]
synonym: "MAPK" RELATED [EC:2.7.11.24, PMID:20811974]
synonym: "MBP kinase I activity" NARROW [EC:2.7.11.24]
synonym: "MBP kinase II activity" NARROW [EC:2.7.11.24]
synonym: "mitogen activated kinase activity" EXACT []
synonym: "mitogen-activated protein kinase activity" EXACT [EC:2.7.11.24]
synonym: "MP kinase activity" NARROW []
synonym: "Mpk2" NARROW []
synonym: "myelin basic protein kinase activity" NARROW [EC:2.7.11.24]
synonym: "p38" NARROW []
synonym: "p38-2" RELATED [EC:2.7.11.24]
synonym: "p38delta" RELATED [EC:2.7.11.24]
synonym: "p42 mitogen-activated protein kinase activity" NARROW [EC:2.7.11.24]
synonym: "p42mapk" RELATED [EC:2.7.11.24]
synonym: "p44mpk" RELATED [EC:2.7.11.24]
synonym: "PMK-1" RELATED [EC:2.7.11.24]
synonym: "PMK-2" RELATED [EC:2.7.11.24]
synonym: "PMK-3" RELATED [EC:2.7.11.24]
synonym: "pp42" RELATED [EC:2.7.11.24]
synonym: "pp44mapk" RELATED [EC:2.7.11.24]
synonym: "SAPK2" NARROW []
synonym: "STK26" RELATED [EC:2.7.11.24]
xref: EC:2.7.11.24
xref: KEGG:R00162
xref: MetaCyc:2.7.11.24-RXN
xref: Reactome:REACT_100829 "ERK5 is activated, Oryza sativa"
xref: Reactome:REACT_104581 "ERK5 is activated, Arabidopsis thaliana"
xref: Reactome:REACT_111161 "Activated ERK1/2 threonine-phosphorylate FRS2alpha., Homo sapiens"
xref: Reactome:REACT_115393 "Phosphorylation of UBF-1:rDNA Promoter, Rattus norvegicus"
xref: Reactome:REACT_12075 "ERK5 is activated, Homo sapiens"
xref: Reactome:REACT_12418 "ERK5 is activated, Rattus norvegicus"
xref: Reactome:REACT_180 "Phosphorylation of UBF-1:rDNA Promoter, Homo sapiens"
xref: Reactome:REACT_25129 "Activation of p38MAPK by DSCAM, Homo sapiens"
xref: Reactome:REACT_29583 "Phosphorylation of UBF-1:rDNA Promoter, Danio rerio"
xref: Reactome:REACT_30765 "Phosphorylation of UBF-1:rDNA Promoter, Canis familiaris"
xref: Reactome:REACT_31584 "Phosphorylation of UBF-1:rDNA Promoter, Bos taurus"
xref: Reactome:REACT_80477 "ERK5 is activated, Danio rerio"
xref: Reactome:REACT_82316 "Activation of p38MAPK by DSCAM, Rattus norvegicus"
xref: Reactome:REACT_83043 "ERK5 is activated, Xenopus tropicalis"
xref: Reactome:REACT_87321 "ERK5 is activated, Mus musculus"
xref: Reactome:REACT_91897 "ERK5 is activated, Bos taurus"
xref: Reactome:REACT_98528 "ERK5 is activated, Canis familiaris"
xref: Reactome:REACT_99483 "ERK5 is activated, Dictyostelium discoideum"
xref: Reactome:REACT_99569 "Phosphorylation of UBF-1:rDNA Promoter, Mus musculus"
is_a: GO:0004702 ! receptor signaling protein serine/threonine kinase activity

AmiGO

Child Terms

This term has the following 7 child terms, out of 7 total.

• [  ] GO:0008338 ! MAP kinase 1 activity
• [  ] GO:0016908 ! MAP kinase 2 activity
• [+] GO:0016909 ! SAP kinase activity (2)
• [  ] GO:0038067 ! MAP kinase activity involved in cell wall biogenesis
• [  ] GO:0038071 ! MAP kinase activity involved in conjugation with cellular fusion
• [  ] GO:0038075 ! MAP kinase activity involved in innate immune response
• [  ] GO:0038079 ! MAP kinase activity involved in osmosensory signaling pathway

Pages in category "GO:0004707 ! MAP kinase activity"

The following 171 pages are in this category, out of 171 total.