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Category:GO:0004663 ! Rab geranylgeranyltransferase activity
name: Rab geranylgeranyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375]
synonym: "geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT []
synonym: "GGTase-II activity" EXACT []
synonym: "GGTaseII activity" EXACT []
synonym: "protein geranylgeranyltransferase type II activity" EXACT []
synonym: "Rab-protein geranylgeranyltransferase activity" EXACT []
synonym: "RabGGTase activity" EXACT []
synonym: "type II protein geranyl-geranyltransferase activity" RELATED [EC:2.5.1.60]
xref: EC:2.5.1.60
xref: MetaCyc:RXN-19995
xref: MetaCyc:RXN-19996
xref: MetaCyc:RXN-19997
is_a: GO:0004661 ! protein geranylgeranyltransferase activity
AmiGO
<GOterm>GO:0004663</GOterm>
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Pages in category "GO:0004663 ! Rab geranylgeranyltransferase activity"
The following 3 pages are in this category, out of 3 total.